Royal Air Force Typhoon fighter aircraft have conducted a mission with French aircraft in a joint strike targeting an hidden munitions depot in Syrian territory employed by the IS group, according to the UK's MoD.
The location, located using intelligence, was assessed as housing weapons and explosive materials, the release indicated, and was positioned in hills just above the historic site of Palmyra in the heart of Syria.
"The RAF jets utilized laser-guided Paveway IV weapons to target a several entry passages down to the facility... preliminary assessments suggest the objective was successfully hit," the MoD said.
There was no indication of any civilian casualties in the strike late on Saturday and all the aircraft returned safely, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
IS - referred to as Daesh - enforced militant control over parts of both Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and determination to work closely with our partners, to stamp out any resurgence of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary John Healey stated.
British military aircraft have performed overwatch operations over Syria to "prevent any efforts to regroup" of Islamic State following its military defeat at the Baghuz confrontation in 2019, the MoD reported.
"I must thank the personnel of the UK armed forces involved in this strike for their professionalism and their bravery," he said. "They were part of a great many British personnel on duty over the festive period. This mission, to take out dangerous terrorists who pose a risk to our way of life, demonstrates how UK forces are ready to step up, throughout the year, ensuring Britain's security domestically and influential overseas."
During December, the United States armed forces conducted what it called a "massive strike" on Daesh sites in the country, subsequent to an attack killed two American soldiers and a civilian linguist in the Palmyra area.
The United Nations reports Islamic State still maintains an estimated 5,000 to 7,000 militants in Syria and Iraq.